Exerpts from the John F. Kennedy Library website:

Shortly after noon on November 22, 1963, President John F. Kennedy was assassinated as he rode in a motorcade through Dealey Plaza in downtown Dallas, Texas…

Crowds of excited people lined the streets and waved to the Kennedys. The car turned off Main Street at Dealey Plaza around 12:30 p.m. As it was passing the Texas School Book Depository, gunfire suddenly reverberated in the plaza.

Bullets struck the president’s neck and head and he slumped over toward Mrs. Kennedy. The governor was also hit in the chest.  The car sped off to Parkland Memorial Hospital just a few minutes away. But little could be done for the President. A Catholic priest was summoned to administer the last rites, and at 1:00 p.m. John F. Kennedy was pronounced dead…

President Kennedy’s flag-draped casket was moved from the White House to the Capitol on a caisson drawn by six grey horses, accompanied by one riderless black horse. At Mrs. Kennedy’s request, the cortege and other ceremonial details were modeled on the funeral of Abraham Lincoln. Crowds lined Pennsylvania Avenue and many wept openly as the caisson passed. During the 21 hours that the president’s body lay in state in the Capitol Rotunda, about 250,000 people filed by to pay their respects.

On Monday, November 25, 1963 President Kennedy was laid to rest in Arlington National Cemetery. The funeral was attended by heads of state and representatives from more than 100 countries, with untold millions more watching on television…

As people throughout the nation and the world struggled to make sense of a senseless act and to articulate their feelings about President Kennedy’s life and legacy, many recalled these words from his inaugural address:

“All this will not be finished in the first one hundred days, nor in the first one thousand days, nor in the life of this administration. Nor even perhaps in our lifetime on this planet. But let us begin.”…

Read a fuller account here:  http://www.jfklibrary.org/JFK/JFK-in-History/November-22-1963-Death-of-the-President.aspx?p=3